{"id":265,"date":"2019-12-22T04:45:39","date_gmt":"2019-12-22T04:45:39","guid":{"rendered":"https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/?page_id=265"},"modified":"2019-12-22T04:52:07","modified_gmt":"2019-12-22T04:52:07","slug":"biomedical","status":"publish","type":"page","link":"https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/biomedical\/","title":{"rendered":"Investigation of Biomedical Flows"},"content":{"rendered":"<figure id=\"attachment_268\" aria-describedby=\"caption-attachment-268\" style=\"width: 319px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-268\" src=\"https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/files\/2019\/12\/biomedical.png\" alt=\"\" width=\"319\" height=\"481\" srcset=\"https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/files\/2019\/12\/biomedical.png 608w, https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/files\/2019\/12\/biomedical-199x300.png 199w, https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/files\/2019\/12\/biomedical-580x874.png 580w, https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/files\/2019\/12\/biomedical-133x200.png 133w, https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/files\/2019\/12\/biomedical-266x400.png 266w\" sizes=\"auto, (max-width: 319px) 100vw, 319px\" \/><figcaption id=\"caption-attachment-268\" class=\"wp-caption-text\">Airflow within realistic human airway. Computation geometry (top-left), mesh (top-right), and vortical structures within airways (bottom).<\/figcaption><\/figure>\n<h3>Summary<\/h3>\n<p>This research effort focuses on numerical investigation of airflow dynamics and aerosol deposition in realistic human airways to understand regional deposition of drugs used for the treatment of pulmonary diseases.<\/p>\n<h3>Support<\/h3>\n<p>The work is supported by the inter-institutional collaborative research pilot grant program referred to as Biomedical Research Initiation Collaborative (<a href=\"https:\/\/www.utc.edu\/research-sponsored-programs\/funding-opportunities\/internal-competitions.php#Erlanger\">BRICS<\/a>) Grant.<\/p>\n<h3><strong>Collaborators<\/strong><\/h3>\n<p><a href=\"https:\/\/www.erlanger.org\/find-a-doctor\/find-a-doctor?id=1368\">Dr. Jigme Sethi<\/a> (UTCOM)<\/p>\n<p><a href=\"https:\/\/www.utc.edu\/faculty\/abdollah-arabshahi\/\">Dr. Abi Arabshahi<\/a> (SimCenter@UTC)<\/p>\n<h3>Test Cases<\/h3>\n<ul>\n<li><a href=\"https:\/\/www.kbwiki.ercoftac.org\/w\/index.php?title=Abstr:AC7-01\">SimInhale Benchmark Case<\/a><\/li>\n<li>CT Scan of a Real Patient<\/li>\n<\/ul>\n<h3>Computational Approaches<\/h3>\n<div class=\"page\" title=\"Page 1\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p>The computational framework employs the well-established Eulerian-Lagrangian strategy where an Eulerian approach is used to simulate the airflow and a Lagrangian approach is used to obtain the aerosol dynamics. First a validation study will be performed by simulating the SimInhale benchmark case and comparing results with the in vitro measurements. Afterward, the framework will be used to examine the effects of the injection flow rate and the injection type (monodisperse <em>versus<\/em> polydisperse) on the regional deposition fraction. Finally, the framework will be used to analyze the regional deposition in a realistic model obtained through a high-resolution computerized tomography scan and the results will be compared with the benchmark case.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h3>Publications<\/h3>\n","protected":false},"excerpt":{"rendered":"<p>Summary This research effort focuses on numerical investigation of airflow dynamics and aerosol deposition in realistic human airways to understand regional deposition of drugs used for the treatment of pulmonary diseases. Support The work is supported by the inter-institutional collaborative research pilot grant program referred to as Biomedical Research Initiation Collaborative (BRICS) Grant. Collaborators Dr.&hellip; <\/p>\n<p class=\"more-link-wrap\"><span><a class=\"more-link button text\" href=\"https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/biomedical\/\"><span>Continue Reading <\/span><\/a><\/span><\/p>\n","protected":false},"author":1459,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"class_list":{"0":"post-265","1":"page","2":"type-page","3":"status-publish","5":"entry","6":"has-post-thumbnail"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Investigation of Biomedical Flows - Reetesh Ranjan Archive<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogarchive.utc.edu\/reetesh-ranjan\/biomedical\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Investigation of Biomedical Flows - Reetesh Ranjan Archive\" \/>\n<meta property=\"og:description\" content=\"Summary This research effort focuses on numerical investigation of airflow dynamics and aerosol deposition in realistic human airways to understand regional deposition of drugs used for the treatment of pulmonary diseases. 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